Opus and XY.AI Announce Strategic Partnership to Bring Agentic Workflow Automation to Behavioral Health and SUD Providers
Opus, the leading purpose-built EHR, CRM, and RCM platform for substance use disorder and behavioral health operators, becomes the first in its category to deliver natively integrated AI agent automation — powered by XY.AI Labs
DENVER, CO — May 4, 2026 — Opus, the leading purpose-built EHR, CRM, and RCM platform designed exclusively for substance use disorder (SUD) and behavioral health treatment providers, today announced a channel partnership with XY.AI Labs, an AI-native, category-defining company for the mid-sized healthcare market that delivers purpose-built agents that automate complex clinical and administrative workflows. The partnership makes Opus the first platform in its category to offer natively integrated agentic automation — combining the most comprehensive operational infrastructure in behavioral health with XY AI’s intelligent agent layer to eliminate the manual burden that has long slowed down growing organizations.
Opus powers thousands of patient encounters daily across hundreds of behavioral health and SUD organizations throughout the United States and Canada. The company is on a mission to help its customers deliver world-class patient care to 4 million patients by 2028. The XY AI partnership directly accelerates that mission.
Closing the Automation Gap in Behavioral Health
Behavioral health and SUD providers operate in one of the most documentation-intensive, compliance-sensitive environments in all of healthcare — and most are still managing it manually. Opus was built by former treatment center operators to solve exactly that problem, replacing the fragmented systems, spreadsheets, and disconnected tools that consume staff capacity and drain revenue. With XY AI now integrated into the platform, Opus extends that solution further: XY AI’s agents handle the repetitive, high-volume tasks — data entry, claims management, scheduling coordination, payment posting, patient onboarding — that previously required hours of manual work every day.
“The operators we serve are under-resourced and over-burdened,” said Humberto Buniotto, CEO and Founder of Opus. “They got into this work to help others, not to spend their days on grunt work. Most of them don’t yet realize how much of what slows them down can be automated. Integrating XY AI’s agents directly inside Opus allows our customers to automate the work that has been holding them back and double down on what they do best.”
The First Agentic Integration in Purpose-Built Behavioral Health Technology
The Opus–XY.AI integration will combine direct API connectivity with browser agent navigation, meaning XY.AI's agents connect to the Opus platform through multiple access points without requiring custom development from the provider.. Behavioral health organizations already on Opus can activate XY AI’s automation capabilities without switching systems, retraining staff, or managing a separate vendor relationship. The result is a single, connected operating environment — clinical, financial, operational, and now fully automated.
“Behavioral health is one of the most underserved areas when it comes to intelligent automation,” said Lamara De Brouwer, Co-Founder and CTO at XY.AI Labs. “Our agents are built specifically for the complexity of healthcare workflows — not retrofitted from generic tools. Partnering with Opus gives us a direct path to operators who are ready to deploy automation inside the platform they already trust. The integration makes the experience seamless from day one, and the impact is immediate.”
What’s Next: Live Demonstration Webinar, June 2026
Opus and XY.AI will co-host a joint webinar in June 2026 featuring a live demonstration of AI agent automation running inside the Opus platform. The session will show behavioral health operators exactly how the integration works in practice — from automated claims management and scheduling coordination to patient onboarding and payment posting — and how providers can activate it without disrupting existing workflows. Registration details will be announced via both companies’ channels.
About Opus
Opus is the all-in-one EHR, CRM, and revenue cycle management platform purpose-built for substance use disorder and behavioral health treatment providers. Founded by former operators, Opus replaces fragmented systems with a single, integrated solution that spans the full patient lifecycle, from admission through billing and alumni engagement. Opus serves treatment providers across the United States and Canada and is committed to helping its customers deliver world-class care to 4 million patients by 2028.
About XY.AI Labs
XY.AI Labs is an AI-native company building agentic AI infrastructure for healthcare operations, focused on the small and mid-sized organizations that make up the long tail of the healthcare system. Its platform combines AI agents with orchestration and intelligence layers to automate workflows across revenue cycle, patient operations, and administrative systems. Designed for fragmented environments, XY.AI integrates with existing systems and uses a proprietary multimodal browser agent where APIs are unavailable.
Co-founded by Lamara De Brouwer and Sam De Brouwer, the company addresses inefficient, manual operations by delivering real-world automation with human-in-the-loop oversight, enabling reliable, scalable, and compliant outcomes for underserved healthcare providers and operators.
Media Contacts
Cy Nelson, Marketing Manager — Opus Behavioral Health
cnelson@opusehr.com
Sam De Brouwer, CEO — XY.AI Labs
sam@xy.ai
